https://unilogia.su/index.php?action=history&feed=atom&title=Mendelian_error 2026-04-08T21:54:21Z История изменений этой страницы в вики MediaWiki 1.44.2 https://unilogia.su/index.php?title=Mendelian_error&diff=888&oldid=prev 2025-11-13T18:00:19Z

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Admin https://unilogia.su/index.php?title=Mendelian_error&diff=887&oldid=prev 2025-03-26T17:00:31Z

<p>Cleaned up using <a href="/index.php?title=WP:AutoEd&amp;action=edit&amp;redlink=1" class="new" title="WP:AutoEd (страница не существует)">AutoEd</a></p> <p><b>Новая страница</b></p><div>{{Short description|Error in the mendelian inheritance}}<br /> {{Refimprove|date=July 2008}}<br /> A &#039;&#039;&#039;Mendelian error&#039;&#039;&#039; in the [[Genetics|genetic]] analysis of a species, describes an [[allele]] in an individual which could not have been received from either of its biological parents by [[Mendelian inheritance]]. Inheritance is defined by a set of related individuals who have the same or similar [[phenotype]]s for a locus of a particular gene. A Mendelian error means that the very structure of the inheritance as defined by analysis of the parental genes is incorrect: one parent of one individual<br /> is not actually the parent indicated; therefore the assumption is that the parental information is incorrect.&lt;ref&gt;<br /> {{cite web<br /> |url=http://www.inra.fr/mia/T/degivry/Schiex05a.pdf<br /> |title=Mendelian error detection in complex pedigree using weighted constraint satisfaction techniques<br /> |publisher=209.85.165.104<br /> |accessdate=2015-08-13<br /> |last=<br /> |first=<br /> }}<br /> &lt;/ref&gt;<br /> <br /> Possible explanations for Mendelian errors are [[genotyping]] errors, erroneous assignment of the individuals as relatives, or [[De novo mutation|de novo]] mutations. Mendelian error is established by demonstrating the existence of a trait which is inconsistent with every possible combination of [[genotype]] compatible with the individual. This method of determination requires [[Pedigree chart|pedigree]] checking, however, and establishing a contradiction between phenotype and pedigree is an [[NP-complete]] problem. Genetic inconsistencies which do not correspond to this definition are Non-Mendelian Errors.<br /> <br /> Statistical genetics analysis is used to detect these errors and to detect the possibility of the individual being linked to a specific disease linked to a single gene. Examples of such diseases in humans caused by single genes are [[Huntington&#039;s disease]] or [[Marfan syndrome]].&lt;ref&gt;<br /> {{cite web<br /> |url=http://bioinf.wehi.edu.au/folders/melanie/statgenhowto.html<br /> |title=Statistical Genetics Analysis<br /> |publisher=bioinf.wehi.edu.au<br /> |accessdate=2008-07-13<br /> |last=<br /> |first=<br /> }}<br /> &lt;/ref&gt;<br /> <br /> == See also ==<br /> * [[Gregor Mendel]]<br /> * [[SNP genotyping]]<br /> <br /> ==Footnotes==<br /> {{reflist}}<br /> * [http://www.inra.fr/mia/T/degivry/Schiex05a.pdf Mendelian error detection in complex pedigree using weighted constraint satisfaction techniques]<br /> <br /> [[Category:Genetics]]<br /> [[Category:Gregor Mendel|error]]<br /> [[Category:NP-complete problems]]<br /> <br /> {{genetics-stub}}</div>

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